Tetracyclic Heteroaromatic Systems-Synthesis of Ethoxycarbonylphenylpyrido[3',2':5,6] Thiopyranoquinolines

Synthesis of Ethoxycarbonylphenyl

  • Muhammad Naeem Khan Department of Chemistry, Government College of Science, Wahdat Road, Lahore, Pakistan
  • Misbahul Ain Khan Department of Chemistry, The Islamia University of Bahawalpur, Pakistan
  • Noreen Aslam Department of Chemistry, Govt. Sadiq College for Women University, Bahawalpur, Pakistan
  • Pir Bakhsh Khan Pakistan Council of Scientific and Industrial Research Laboratories Complex, Lahore, Pakistan
  • Ehsan ul Haq Pakistan Council of Scientific and Industrial Research Laboratories Complex, Lahore, Pakistan
Keywords: thiopyranoquinolines, synthesis of ethoxycarbonyl, Schiff's bases

Abstract

7-benzylideneamino-5H-thiochromeno[2,3-b]pyridin-5-ones and 9-benzylideneamino-5H-thio- chromeno[2,3-b]pyridin-5-ones, on reaction with ethyl pyruvate to afford 1-ethoxycarbonyl-3-phenyl-12H- pyrido[3',2':5,6]thiopyrano[3,2-f]quinoline-12-ones and 4-ethoxycarbonyl-2-phenyl-7H- pyrido[3',2':5,6]thiopyrano[3,2-h]quinoline-7-ones respectively by the two different methods. These products were precipitated by addition of ethanol, water (1:1), were purified by recrystalizing from appropriate solvents and were characterized from their IR, 1H-NMR, mass spectra and elemental analysis data.

 

Published
2021-09-28