Preliminary Study on the Role of Medicinal Plant Tinospora cordifolia in Reducing Bacterial Load from Human Hand

Bacteria Removing from Human Hand by Medicinal Plant

Abstract

Excessive and unregulated application of antimicrobial agents stands at the forefront as the major instigator for the development of bacterial strains exhibiting resistance to multiple drugs, commonly referred to as multi-drug resistance (MDR). In addition, synthetic drugs are more expensive for the treatment of diseases. Additionally, the cost of using synthetic medications to treat illnesses is much higher. Therefore, in order to control microbial infections, new infection-fighting techniques must be developed. The study was planned to evaluate the role of Tinospora cordifolia against various bacterial strains. In total of 500 samples were collected randomly from people working in university of Swabi and tested for presence of bacterial load. Three bacterial strains were isolated i.e., Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa. The anti-bacterial profile of isolated strains was determined using Ciprofloxacin, Tetracycline, Erythromycin, Ampicillin, Chloramphenicol and Amoxicillin. The activity Tinospora cordifolia was evaluated against antibiotic resistant bacterial strains which showed inhibitory activity against various multi-drug resistance bacterial strains and these results were compared with already available antibiotics. The results of antibiotic profiling showed that the Ciprofloxacin and Tetracycline were most efficient against all strains with a largest zone of inhibition followed by Chloramphenicol while Erythromycin, Ampicillin and Amoxicillin show no zones of inhibition. Whereas the activity of the medicinal plant extract of Tinospora cordifolia showed inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. It is concluded that the Tinospora cordifolia have antibacterial potential and uphold its replacement with of commonly used antibiotic drugs.