Efficacy Studies of Two Iron Supplements Irovit-1 and Irovit-2

Studies of Iron Supplements

  • Rehana Jafri Pharmaceutical Research Centre, Pakistan Council of Scientific and Industrial Research Laboratories Complex, Karachi - 75280, Pakistan
  • Amir Ahmed Pharmaceutical Research Centre, Pakistan Council of Scientific and Industrial Research Laboratories Complex, Karachi - 75280, Pakistan
  • Kamran Abro Pharmaceutical Research Centre, Pakistan Council of Scientific and Industrial Research Laboratories Complex, Karachi - 75280, Pakistan
  • Irshad Ahmed Khan Pharmaceutical Research Centre, Pakistan Council of Scientific and Industrial Research Laboratories Complex, Karachi - 75280, Pakistan
  • Atiq ur Rehman Pharmaceutical Research Centre, Pakistan Council of Scientific and Industrial Research Laboratories Complex, Karachi - 75280, Pakistan
Keywords: iron saccharate, oral supplements, efficacy hemoglobin level

Abstract

Two preparations of iron supplements have been developed with vitamins, Irovit-1 and Irovit-2 containing 1 mg/mL and 2 mg/mL elemental iron respectively in complex form. Clinical trials of Irovit-1 and Irovit-2 have been conducted randomly on selected anemic males and females from urban population of Karachi, an improvement in hemoglobin levels were estimated for the treatments with Irovit-1 (10 mg Fe/day) and Irovit-2 (20 mg Fe/day). Both preparations have been found to be effective in increasing hemoglobin, Hematocrit and red blood cell count. The mean hemoglobin levels were observed increased 0.73 ± 0.25 g/dL and 1.10 ± 0.30 g/dL, after 5 weeks by oral intake of Irovit-1 and Irovit-2, respectively.

 

Published
2021-03-01